Review Artikel: Aktivitas Antiulcer Dari Tanaman Famili Zingiberaceae

Abstract

Peptic ulcer is commonly known as gastrointestinal disease due to disturbance of
normal equilibrium caused by an increase or decrease in mucosal ulceration resistance.
The main risk factors for peptic ulcers are Helicobacter pylori infection and the use of
non-steroidal anti-inflammatory drugs (NSAIDs). Prevention or treatment of peptic
ulcers can be done by using medicinal plants that have an antiulcer effect. One of the
plant families that has great potential to be used as medicine is the Zingiberaceae
family, which has a gastroprotective effect. This review article was compiled with the
aim of determining plants with antiulcer potential from the Zingiberaceae family.
Literature study was conducted on national and international journals related to
Zingiberaceae family plants that have antiulcer activity, published in the last 10 years.
Referring to the results of the literature study, 8 plants of the Zingiberaceae family were
successfully identified as having potential as antiulcer, including Zingiber Officinale
plants with the active compound of 6-gingesulfonic acid; Zingiber cassumunar with the
active compounds of alkaloids, flavonoids, saponins, tannins, quinones, and steroids;
Curcuma xanthorrhiza with the active compound of curcuminoid; Curcuma longa with the active compound of curcumin; Alpinia galang with the active compound of 1’acetoxy
chavicol acetate, flavonoids and saponins; Kaempferia galanga with the active
compound of p-methoxy cinnamic acid; Aframomum melegueta with the active
compound of 6-Paradol; and Elettaria Cardamomum with the active compound of αphellandrene.