Uji Konfirmasi Morfin dengan Metode KLT
Article Sidebar
Main Article Content
Abstract
Morphine is one of the opiate analgesic drugs. Morphine has dependent properties. So it is forbidden to use without a doctor's prescription. Is an opiate compound and determines the type of opiate compound, namely morphine. In 14 reviewed journals, the results stated that the analysis of morphine in samples using the TLC method gave good and sensitive results.
Article Details
References
Ahadia, A., A. Partoazarb, M. A. Khorasganic, S. V.S.Boushehrid. Comparison of
Liquid-Liquid Extraction-Thin Layer Chromatography With Solid-Phase ExtractionHigh-Performance Thin Layer Chromatography in Detection Of Urinary Morphine.
Journal of Biomedical Research. 2011; 25(5):362-367
Basiri, R. M., M. Ghazi-khansari, A. Faghih, M. Sadeghi, N. Lotfalizadeh, M. Eghba, A.
Mohajell-Nayebi, H. Rezazadeh , M. Arshad Zadeh. Screening of Morphine &
Codeine in Urine of Opioid Abusers by Rapid and TLC Analysis. European Journal
of General Medicine. 2010; 7(2):192-196
Badan Narkotika Nasional. Urine Screening System.2016.
Budd RD, Mathis DF, Leung WJ. Screening and ConfirmaTion Of Opiates By ThinLayer Chromatography. Clin Toxicol. 1980; 16(1):61-6.
Chandrayani,L.P. Ari N.P. Linda L., I.N.K. Widjaja. Derivatisasi Morfin Menggunakan
Dansil Klorida untuk Meningkatkan Kepekaan Deteksi Morfin pada Metode KLTspektrofotodensitometer. Jurnal Farmasi Udayana. 2012; 1(1): 1-8.
De, S., R. Choudhary, R. Madhuri. Deterination of Morphine in Urine. India:
Departement t of Applied Chemistry, Indian Institute of Technology (Indian School
of Mines). 2019.
Dewi, N.P. D. K., N.W. I. Indayanti, I. K. N. Sanjaya, A. A. I. K. Dewi, dan N.P.L.
Laksmiani. Screening and Determination of Opiates in Human Urine Samples By
Immunoassay And TLC –Spectrophotodensitometry. Indonesian Journal of Legal
and Forensic Sciences. 2019; 9(2): 82-88.
Esmaiili and S. V. S.Boushehri. Comparative Verification Study Of Silica Gel-Coated
TLC And HPTLC Plates’ Performances In Separation Of Opium Alkaloids on the
Basis Of Their Physicochemical Properties. Journal of Analytical Science and
Technology. 2017; 8:22.
Fifield, F.W. and D. Kealey, Principles and Practice of Analytical Chemistry. Fifth
Edition. USA: Blackwell Science. 2000.
Gandjar, I. G. dan A. Rohman. Kimia Analisis Farmasi. Yogyakarta: Pustaka Pelajar.
Gandjar, I. G. dan A. Rohman. Analisis Obat. Yogyakarta: Pustaka Pelajar. 2012.
Hariri, A. T., M. Balali-Mood, M. Sadeghi, N. Lari, B. R.Zanjani. Comparison of ELISA
and TLC Methods for the Morphine Detection in Urine of Drug Abusers. Iranian
Journal of Toxicology. 2016; 10(3): 47-50
Howland, R. D., Mary, J. M., Richard, A. H. and Pamela, C. C. Lippincott’s Illustrated
Reviews: Pharmacology. 3rd Edition. Philadelphia: Lippincott Williams & Wilkins.
Kemenkes RI. Farmakope Indonesia. Edisi V. Jakarta: Kementrian Kesehatan Republik
Indonesia. 2014.
Moffat, A. C., M. D. Osselton and B. Widdop. Clarke’s Analysis of Drugs and Poisons.
th Edition. London: Pharmaceutical Press. 2005.
Moffat, A. C., M. David, O., and Brian, W. Clarke’s Analysis of Drugs and Poisons.
Fourth Edition. London: Pharmaceutical Press. 2011.
Popa, D. S., R. Oprean, E. Curea, N. Preda. TLC-UV densitometric and GC-MSD
methods for simultaneous quantification of morphine and codeine in poppy capsules.
Journal of Pharmaceutical and Biomedical Analysis. 1998; 18: 645–650
O’g’li, E. F, B., Y. E. Gaynatovna, P. G. Aliksandrovna, S. S. Anarmatovich, A. S.
Sadikovna. Obtaining Of Morphine-Bsa Conjugate for Using In Elisa As An
Antigen For Sorbsion. European Science Review. 2019; 16-20.
Sadock BJ, Saddock VA. Kaplan & Sadock's Synopsis of Psychiatri : Behavior Sciences/
Clinical Psychiatric. 10th ed. Philadelphia: Lippincott Williams & Wilkins. 2007.
Sherma, J. and B. Fried. Handbook of Thin-Layer Chromatography. Third Edition. New
York: Marcel Dekker Inc. 1994.
Heri, A. A. P. dan A. Subarnas. Morfin: Penggunaan Klinis dan Aspek-aspeknya.
Farmaka. 2020; 17(3): 134-141
Tames, F., I. D. Watson, W. Morden, I. D. Wilson. Detection and Identification of
Morphine in Urine Extracts Using Thin-Layer Chromatography and Tandem Mass
Spectrometry. Journal of Chromatography B. 1999; 729: 341–346.
Trescot, A. M., Datta, S., Lee, M. and Hansen, H. Opioid Pharmacology. Pain Physician.
;11 : 133-153
Widjaja, I N.K., Ni M. P. Susanti, Ni P. Linda Laksmiani dan K. D. Cahyadi. Petunjuk
Praktikum Kimia Analisis. Bukit Jimbaran: Jurusan Farmasi Fakultas Matematika
dan Ilmu Pengetahuan Alam Universitas Udayana. 2014.
Wirasuta,I M. A. G., I. A. S. Primaningruma, K. W. Astutia. Uji Konfirmasi dan
Penetapan Kadar Morfin dengan KLT-Spektrofotodensitometri. Indonesian Journal
of Legal and Forensic Sciences. 2014; 4:5-7
Verma, K. L., M. Kumar, A. P. Singh. HPTLC-MS as a Neoteric Hyphenated Technique
for Separation and Forensic Identification of Drugs. Journal of Analytical Sciences,
Methods and Instrumentation.2018; 8: 1-15
Wallace, J. E., J. D. Biggs, J. H. Merritt, H. E. Hamilton. K. Blum. A sensitive ThinLayer Chromatography Techique for Determining Morphine in Urine. Journal of
Chromatography A. 1972; 71: 135-140.
Wirasuta, I.M.A.G. Analisis Toksikologi Forensik dan Interpretasi Temuan Analisis.
Indonesian Journal of Legal and Forensic Sciences. 2008; 1(1): 47 – 55.
Wirasuta,I M. A. G., I. A. S. Primaningruma, K. W. Astutia. Uji Konfirmasi dan
Penetapan Kadar Morfin dengan KLT-Spektrofotodensitometri. Indonesian Journal of
Legal and Forensic Sciences.2014; 4: 5-7.